Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429802 | 1.00 | ALDH1A1 (0.42) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL24118131 | 0.84 | PTPN5 (0.47) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL414157 | 0.78 | ALDH1A1 (0.53) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL29746207 | 0.78 | ALDH1A1 (0.53) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL25798292 | 0.77 | GABRB3 (0.36) | ALDH1A1HPGDHSD17B10TSHRGABRB3 | |
| SCHEMBL18299676 | 0.77 | PTPN5 (0.41) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL9217763 | 0.77 | ALDH1A1 (0.43) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| Hydrochloric Acid SCHEMBL8947519 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PTPN5KDM4EPKMHPGD | |
| SCHEMBL23899710 | 0.75 | CHEK1 (0.37) | ALDH1A1HPGDHSD17B10TSHRMEN1 | |
| SCHEMBL14054165 | 0.75 | GABRB3 (0.38) | ALDH1A1KDM4EHPGDTSHRGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526309-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | Genentech, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-119365467-A | Aza-tetraepoxy aza compounds and uses thereof | 基因泰克公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2023225302-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2023-11-23 | — | — | WO | disclosed |