Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357465 | 1.00 | MAPT (0.36) | MAPTPOLBHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL27072904 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1IRAK4GAA | |
| SCHEMBL30711996 | 0.79 | ALDH1A1 (0.41) | MAPTPOLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL23357368 | 0.79 | ALDH1A1 (0.41) | MAPTPOLBSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL5961491 | 0.73 | ADORA2A (0.38) | MAPTPOLBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25386715 | 0.73 | MEN1 (0.33) | MAPTHTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL20674173 | 0.71 | HPGD (0.41) | POLBHTTKDM4EALDH1A1HPGD | |
| SCHEMBL16887703 | 0.70 | TP53 (0.43) | CYP11B2IRAK4TP53 | |
| SCHEMBL22337069 | 0.70 | CYP11B2 (0.33) | MAPTKDM1ACYP11B2TP53 | |
| SCHEMBL25881445 | 0.70 | S1PR2 (0.36) | MAPTALDH1A1MAPK1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869363-B | 5-membered and bicyclic heterocyclic amides as ROCK inhibitors | 百时美施贵宝公司 | 2024-01-05 | — | — | CN | disclosed |