SCHEMBL30712396

SCHEMBL30712396

[2H]C([2H])([2H])Oc1cc(F)ccc1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTR1A P08908 1/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1A P35348 1/20 0.46
ADRA1B P35368 1/20 0.46
ENPP2 Q13822 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MRGPRX4 Q96LA9 1/20 0.45
ABCB1 P08183 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21667956 0.89 FFAR1 (0.58) FFAR1FFAR4L3MBTL1MAPTMAPK1
SCHEMBL3232989 0.85 HTR1A (0.58) L3MBTL1MAPTMAPK1TDP1NPC1
SCHEMBL30002764 0.83 FFAR1 (0.66) FFAR1FFAR4L3MBTL1MAPTMAPK1
SCHEMBL4228617 0.83 FFAR1 (0.66) FFAR1FFAR4L3MBTL1MAPTMAPK1
SCHEMBL23582260 0.81 HTR1A (0.59) FFAR1FFAR4L3MBTL1MAPTMAPK1
SCHEMBL29914010 0.81 HTR1A (0.59) FFAR1FFAR4L3MBTL1MAPTMAPK1
SCHEMBL31040308 0.81 NPC1 (0.52) MAPTNPC1RAB9AHPGDSMN1; SMN2
SCHEMBL31040310 0.78 KDM4E (0.54) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL30028779 0.78 ALDH1A1 (0.61) MAPTNPC1RAB9AHPGDSMN1; SMN2
SCHEMBL4750249 0.78 PTGER4 (0.53) MAPTNPC1RAB9AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521399-B2 Compound as voltage-gated sodium channel inhibitor GUANGZHOU FERMION TECHNOLOGY CO., LTD. (CN) 2026-01-13 US disclosed
EP-4570788-A1 COMPOUND AS VOLTAGE-GATED SODIUM CHANNEL INHIBITOR Guangzhou Fermion Technology Co., Ltd. (CN) 2025-06-18 EP disclosed
WO-2024032774-A1 COMPOUND AS VOLTAGE-GATED SODIUM CHANNEL INHIBITOR 广州费米子科技有限责任公司 2024-02-15 WO disclosed