Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30713208 | 0.87 | KDM4E (0.39) | MAPTHDAC8HDAC3NCOR1HDAC1 | |
| SCHEMBL30687474 | 0.85 | HTT (0.33) | HTTMAPTNPSR1HDAC8HDAC3 | |
| SCHEMBL30713258 | 0.82 | HTT (0.37) | HTTMAPTNPSR1HDAC8HDAC3 | |
| SCHEMBL30713218 | 0.82 | NPC1 (0.42) | MAPTNPSR1KDM4EMEN1KMT2A | |
| SCHEMBL30713203 | 0.74 | ALDH1A1 (0.39) | HTTMAPTNPSR1MEN1KMT2A | |
| SCHEMBL31258801 | 0.72 | ALDH1A1 (0.38) | HTTHDAC8HDAC3NCOR1HDAC1 | |
| SCHEMBL31049474 | 0.72 | CXCR2 (0.38) | HTTMAPTHDAC8HDAC3NCOR1 | |
| SCHEMBL30713239 | 0.72 | ALDH1A1 (0.43) | HTTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL31258770 | 0.72 | KDM4E (0.37) | HTTMAPTNPSR1KDM4EMEN1 | |
| SCHEMBL31258741 | 0.71 | EPHB3 (0.38) | MAPTHDAC8HDAC3NCOR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4549438-A1 | FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| CN-117304183-A | Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |