Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258785 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRKDM4EMAPT | |
| SCHEMBL30713208 | 0.86 | KDM4E (0.39) | ALDH1A1MAPK1KDM4EMAPTMEN1 | |
| SCHEMBL30713202 | 0.82 | KMT2A (0.43) | ALDH1A1HPGDTSHRPKML3MBTL1 | |
| SCHEMBL31258770 | 0.80 | KDM4E (0.37) | ALDH1A1HPGDPKMMAPK1KDM4E | |
| SCHEMBL30713218 | 0.77 | NPC1 (0.42) | ALDH1A1HPGDTSHRMAPK1KDM4E | |
| SCHEMBL29267300 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRKDM4ETDP1 | |
| SCHEMBL29267236 | 0.74 | EGLN1 (0.39) | ALDH1A1HPGDPKMKDM4EMAPT | |
| SCHEMBL3165801 | 0.73 | L3MBTL1 (0.52) | ALDH1A1HPGDTSHRPKML3MBTL1 | |
| SCHEMBL31258741 | 0.72 | EPHB3 (0.38) | ALDH1A1MAPK1KDM4EMAPTMEN1 | |
| SCHEMBL30713232 | 0.72 | HTT (0.37) | ALDH1A1HPGDTSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4549438-A1 | FIVE-MEMBERED AND SIX-MEMBERED NITROGEN-CONTAINING COMPOUND, AND INTERMEDIATE, PREPARATION METHOD AND USE THEREOF | Hangzhou Synrx Therapeutics Biomedical Technology Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| CN-117304183-A | Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |