Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22394958 | 1.00 | RARA (0.36) | RARARARBRARGSPHK2NR1H4 | |
| SCHEMBL22394873 | 0.83 | GRM5 (0.41) | — | |
| SCHEMBL23610394 | 0.79 | S1PR1 (0.35) | RARARARBRARGNR1H4HSD11B1 | |
| SCHEMBL22613838 | 0.78 | HSD11B1 (0.38) | RARARARBRARGSPHK2NR1H4 | |
| SCHEMBL29408927 | 0.78 | HSD11B1 (0.38) | RARARARBRARGSPHK2NR1H4 | |
| SCHEMBL22394864 | 0.77 | TRPV1 (0.35) | RARARARBRARGNR1H4TRPV1 | |
| SCHEMBL22394862 | 0.76 | NR1H4 (0.31) | RARARARBRARGNR1H4TRPV1 | |
| SCHEMBL22395381 | 0.76 | ATF4 (0.48) | — | |
| SCHEMBL23610403 | 0.76 | TRPV1 (0.35) | RARARARBRARGNR1H4BDKRB1 | |
| SCHEMBL22394863 | 0.76 | ATF4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204012-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-12-26 | — | — | CN | disclosed |