Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 14/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26923125 | 1.00 | CYP11B2 (0.44) | CYP11B2GLAPOLBGAATSHR | |
| SCHEMBL2652002 | 0.80 | MAP4K4 (0.44) | CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL7085699 | 0.80 | CYP11B1 (0.40) | CYP11B2CYP11B1CYP17A1CYP3A4MEN1 | |
| SCHEMBL30296524 | 0.78 | CYP11B2 (0.41) | CYP11B2GLAPOLBGAATSHR | |
| SCHEMBL26922914 | 0.78 | CYP11B2 (0.44) | CYP11B2TSHRCYP11B1CYP17A1CYP3A4 | |
| SCHEMBL30714465 | 0.78 | ABL1 (0.41) | CYP11B2TSHRCYP11B1CYP17A1CYP3A4 | |
| SCHEMBL26923550 | 0.78 | ABL1 (0.41) | CYP11B2TSHRCYP11B1CYP17A1CYP3A4 | |
| SCHEMBL3784686 | 0.76 | KIF11 (0.58) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL2808894 | 0.75 | TSHR (0.67) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL30714499 | 0.75 | CYP11B1 (0.37) | CYP11B2CYP11B1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536637-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Nico Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023240084-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |