Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652002 | 0.86 | MAP4K4 (0.44) | CYP11B1CYP11B2CYP17A1CYP3A4PARP10 | |
| SCHEMBL7085557 | 0.83 | MEN1 (0.40) | CYP11B1CYP11B2PIK3CAPRKCZROCK2 | |
| SCHEMBL26922914 | 0.83 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP17A1CYP3A4PARP10 | |
| SCHEMBL26923550 | 0.83 | ABL1 (0.41) | CYP11B1CYP11B2CYP17A1CYP3A4PARP10 | |
| SCHEMBL30714465 | 0.83 | ABL1 (0.41) | CYP11B1CYP11B2CYP17A1CYP3A4PARP10 | |
| SCHEMBL30714533 | 0.80 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP17A1CYP3A4MEN1 | |
| SCHEMBL26923125 | 0.80 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP17A1CYP3A4MEN1 | |
| SCHEMBL30714499 | 0.80 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP17A1CYP3A4PARP10 | |
| SCHEMBL26923618 | 0.79 | PARP10 (0.39) | CYP11B1CYP11B2CYP17A1CYP3A4PARP10 | |
| SCHEMBL26923403 | 0.79 | CYP11B2 (0.57) | CYP11B1CYP11B2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |