Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355233 | 0.83 | MKNK1 (0.41) | MKNK1MKNK2SLC9A1P2RX7NPC1 | |
| SCHEMBL30715028 | 0.83 | SLC9A1 (0.44) | SLC9A1P2RX7NPC1MAPTRAB9A | |
| SCHEMBL31355234 | 0.75 | OPRM1 (0.41) | NAPRTSLC9A1P2RX7NPC1MAPT | |
| SCHEMBL30243669 | 0.73 | GPR88 (0.45) | NPC1MAPTRAB9A | |
| SCHEMBL15541759 | 0.71 | KDM1A (0.56) | SLC9A1MAPTKDM1A | |
| SCHEMBL4138471 | 0.71 | KDM1A (0.55) | SLC9A1KDM1A | |
| SCHEMBL4139367 | 0.71 | KDM1A (0.56) | SLC9A1MAPTKDM1A | |
| SCHEMBL15541112 | 0.71 | KDM1A (0.56) | SLC9A1MAPTKDM1A | |
| SCHEMBL31701500 | 0.71 | KDM1A (0.56) | SLC9A1MAPTKDM1A | |
| SCHEMBL4139370 | 0.71 | KDM1A (0.56) | SLC9A1MAPTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396469-A | Inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |