Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667803 | 1.00 | DRD2 (0.32) | DRD2ELANEPDE4BHDAC1HDAC6 | |
| SCHEMBL14402984 | 0.83 | TOP2A (0.33) | DRD2TOP2A | |
| SCHEMBL4984988 | 0.81 | DRD2 (0.34) | DRD2TOP2A | |
| SCHEMBL17781426 | 0.78 | USP8 (0.38) | — | |
| SCHEMBL4981079 | 0.78 | DRD2 (0.33) | DRD2PDE4BTOP2A | |
| SCHEMBL4979480 | 0.76 | BACE1 (0.31) | — | |
| SCHEMBL14188879 | 0.76 | BACE1 (0.31) | — | |
| SCHEMBL31254281 | 0.74 | RXRA (0.32) | — | |
| SCHEMBL24667801 | 0.73 | ALDH1A1 (0.42) | PDE4B | |
| SCHEMBL24667804 | 0.73 | CCR1 (0.42) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412960-A | Isoindolinone compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-01-16 | — | — | CN | disclosed |