SCHEMBL30717031

SCHEMBL30717031

C[Si]1(C)CCN(c2cc(NS(=O)(=O)CCO)ccc2C(=O)Nc2cccc(N3CCC(F)(F)CC3)c2)CC1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27376105 1.00 KIF18A (0.82) KIF18A
SCHEMBL22964484 0.90 KIF18A (1.00) KIF18A
SCHEMBL30716985 0.89 KIF18A (0.65) KIF18A
SCHEMBL27376102 0.89 KIF18A (0.65) KIF18A
SCHEMBL24818200 0.87 KIF18A (0.82) KIF18A
SCHEMBL30717027 0.86 KIF18A (0.83) KIF18A
SCHEMBL27376274 0.86 KIF18A (0.83) KIF18A
SCHEMBL27375643 0.85 KIF18A (0.83) KIF18A
SCHEMBL30717119 0.83 KIF18A (0.60) KIF18A
SCHEMBL30717087 0.82 KIF18A (0.55) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572855-A1 INHIBITORS OF KIF18A AND USES THEREOF Accent Therapeutics, Inc. (US) 2025-06-25 — — EP disclosed
WO-2024039829-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-02-22 — — WO disclosed
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