SCHEMBL30717119

SCHEMBL30717119

C[Si]1(C)CCN(c2cc(NS(=O)(=O)CCO)ccc2C(=O)Nc2cccc(C3(C(F)(F)F)N=N3)c2)CC1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27376105 0.83 KIF18A (0.82) KIF18A
SCHEMBL30717031 0.83 KIF18A (0.82) KIF18A
SCHEMBL27376274 0.79 KIF18A (0.83) KIF18A
SCHEMBL30717027 0.79 KIF18A (0.83) KIF18A
SCHEMBL27375643 0.78 KIF18A (0.83) KIF18A
SCHEMBL30717173 0.78 KIF18A (0.80) KIF18A
SCHEMBL30717111 0.77 KIF18A (0.81) KIF18A
SCHEMBL30717178 0.77 KIF18A (0.81) KIF18A
SCHEMBL30717053 0.77 KIF18A (0.81) KIF18A
SCHEMBL30778512 0.76 KIF18A (0.61) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572855-A1 INHIBITORS OF KIF18A AND USES THEREOF Accent Therapeutics, Inc. (US) 2025-06-25 — — EP disclosed
WO-2024039829-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-02-22 — — WO disclosed
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