SCHEMBL30717665

SCHEMBL30717665

COC(C(=O)N1CCc2nc(N3C4CCC3CN(C(=O)OC(C)(C)C)C4)sc2C1)C1(C)CCCC1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRAMD1A Q96CP6 1/20 0.38
GCK P35557 17/20 0.34
ADORA1 P30542 1/20 0.33
SPR P35270 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717590 0.90 GRAMD1A (0.39) GRAMD1AGCKADORA1SPR
SCHEMBL30717325 0.85 GRM5 (0.32)
SCHEMBL30717601 0.82 GRAMD1A (0.38) GRAMD1AGCKADORA1SPR
SCHEMBL30717629 0.80 GCK (0.43) GRAMD1AGCKADORA1
SCHEMBL30717613 0.79 GRAMD1A (0.41) GRAMD1AGCKADORA1SPR
SCHEMBL30717569 0.78 GRAMD1A (0.39) GRAMD1AGCKADORA1SPR
SCHEMBL30717587 0.76 GRM5 (0.40) GRAMD1AGCKADORA1
SCHEMBL30717462 0.73 GRM5 (0.33)
SCHEMBL30717657 0.72 ADORA1 (0.35) GRAMD1AGCKADORA1SPR
SCHEMBL30717608 0.71 DDB1 (0.37) GRAMD1ASPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572762-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS Mironid Limited (GB) 2025-06-25 EP disclosed
WO-2024038128-A1 COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS MIRONID LIMITED (GB) 2024-02-22 WO disclosed