Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.34 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30717613 | 0.92 | GRAMD1A (0.41) | ADORA1GPR119GRAMD1AUSP30SPR | |
| SCHEMBL30717612 | 0.83 | ADORA1 (0.38) | ADORA1GPR119USP30SPRMAPT | |
| SCHEMBL30717569 | 0.80 | GRAMD1A (0.39) | ADORA1GPR119GRAMD1ASPRMAPT | |
| SCHEMBL30717643 | 0.79 | NR1H2 (0.37) | ADORA1GPR119USP30LIPERET | |
| SCHEMBL30717574 | 0.78 | SPR (0.37) | ADORA1GPR119USP30SPRRET | |
| SCHEMBL30717629 | 0.77 | GCK (0.43) | ADORA1GRAMD1AMAPTGCKSCN4A | |
| SCHEMBL30717602 | 0.77 | GRAMD1A (0.38) | GPR119CYP8B1GRAMD1AGCKRET | |
| SCHEMBL30717608 | 0.76 | DDB1 (0.37) | GPR119GRAMD1AUSP30SPRRET | |
| SCHEMBL30717625 | 0.75 | GRAMD1A (0.44) | ADORA1GPR119GRAMD1AMAPTGCK | |
| SCHEMBL30717601 | 0.75 | GRAMD1A (0.38) | ADORA1GPR119GRAMD1ASPRGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572762-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | Mironid Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038128-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |