SCHEMBL30717872

SCHEMBL30717872

CC(C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)N[N+](=O)[O-])C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.55
▸ OPRM1 P35372 2/20 0.48
▸ OPRD1 P41143 2/20 0.48
▸ OPRK1 P41145 1/20 0.48
▸ IL23R Q5VWK5 2/20 0.48
▸ APC P25054 3/20 0.47
▸ OPRL1 P41146 4/20 0.47
▸ GLP1R P43220 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717824 0.98 TFPI (0.57) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717883 0.96 TFPI (0.51) TFPIOPRK1IL23R
SCHEMBL30717909 0.94 IL23R (0.51) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717863 0.94 TFPI (0.52) TFPIOPRK1IL23R
SCHEMBL30717836 0.94 TFPI (0.50) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717855 0.94 TFPI (0.50) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717920 0.94 TFPI (0.50) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717910 0.93 TFPI (0.54) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717881 0.93 TFPI (0.54) TFPIOPRM1OPRD1OPRK1IL23R
SCHEMBL30717843 0.92 IL23R (0.51) TFPIIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 — — EP disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 — — EP disclosed
WO-2024022332-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2024-02-01 — — WO disclosed
WO-2023202655-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP TFPI 6/4885OPRM1 4813/4885OPRD1 4807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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