SCHEMBL30717836

SCHEMBL30717836

NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)N[N+](=O)[O-])C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.50
▸ APC P25054 3/20 0.48
▸ IL23R Q5VWK5 2/20 0.47
▸ CHRNA1 P02708 1/20 0.47
▸ CHRNG P07510 1/20 0.47
▸ CHRNB1 P11230 1/20 0.47
▸ CHRND Q07001 1/20 0.47
▸ OPRM1 P35372 5/20 0.47
▸ OPRD1 P41143 5/20 0.47
▸ OPRK1 P41145 1/20 0.46
▸ CD40 P25942 1/20 0.45
▸ QRFPR Q96P65 2/20 0.45
▸ GRIA1 P42261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717855 1.00 TFPI (0.50) TFPIAPCIL23RCHRNA1CHRNG
SCHEMBL30717920 1.00 TFPI (0.50) TFPIAPCIL23RCHRNA1CHRNG
SCHEMBL30717881 0.96 TFPI (0.54) TFPIAPCIL23ROPRM1OPRD1
SCHEMBL30717835 0.95 CHRNA1 (0.48) TFPIIL23RCHRNA1CHRNGCHRNB1
SCHEMBL30717824 0.95 TFPI (0.57) TFPIAPCIL23ROPRM1OPRD1
SCHEMBL30717872 0.94 TFPI (0.55) TFPIAPCIL23ROPRM1OPRD1
SCHEMBL30717883 0.92 TFPI (0.51) TFPIIL23RCHRNA1CHRNGCHRNB1
SCHEMBL30717863 0.91 TFPI (0.52) TFPIIL23ROPRK1
SCHEMBL30717899 0.91 IL23R (0.51) TFPIIL23ROPRM1OPRD1OPRK1
SCHEMBL30717830 0.90 OPRD1 (0.52) TFPIAPCCHRNA1CHRNGCHRNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 — — EP disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 — — EP disclosed
WO-2024022332-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2024-02-01 — — WO disclosed
WO-2023202655-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP TFPI 6/4885APC 2/4885IL23R 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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