Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932036 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTNPSR1HPGDKDM4E | |
| SCHEMBL27029473 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTNPSR1HPGDKDM4E | |
| SCHEMBL29931594 | 0.87 | CYP1A2 (0.54) | SMN1; SMN2MAPTNPSR1HPGDKDM4E | |
| SCHEMBL27029490 | 0.86 | CKS1B (0.47) | CKS1BSKP1SKP2GBA1PIK3CA | |
| SCHEMBL30718265 | 0.86 | CKS1B (0.47) | CKS1BSKP1SKP2GBA1PIK3CA | |
| SCHEMBL30718211 | 0.85 | ACHE (0.55) | MAPTCKS1BSKP1SKP2GBA1 | |
| SCHEMBL27029442 | 0.85 | ACHE (0.55) | MAPTCKS1BSKP1SKP2GBA1 | |
| SCHEMBL30718220 | 0.85 | GPR119 (0.51) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 | |
| SCHEMBL30718222 | 0.85 | NPC1 (0.51) | HPGDKDM4EHSD17B10TSHRALDH1A1 | |
| SCHEMBL27029457 | 0.85 | GPR119 (0.51) | SMN1; SMN2HPGDKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |