Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.47 |
| ▸ | SKP1 | P63208 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27029490 | 1.00 | CKS1B (0.47) | CKS1BSKP1SKP2TLR9TLR7 | |
| SCHEMBL27029476 | 0.89 | NPC1 (0.51) | CKS1BSKP1SKP2TLR9TLR7 | |
| SCHEMBL30718222 | 0.89 | NPC1 (0.51) | CKS1BSKP1SKP2TLR9TLR7 | |
| SCHEMBL29931606 | 0.88 | NPC1 (0.45) | PIK3CAMTOR | |
| SCHEMBL27029473 | 0.86 | SMN1; SMN2 (0.52) | CKS1BSKP1SKP2PTPN11PIK3CA | |
| SCHEMBL29932036 | 0.86 | SMN1; SMN2 (0.52) | CKS1BSKP1SKP2PTPN11PIK3CA | |
| SCHEMBL30718262 | 0.86 | SMN1; SMN2 (0.52) | CKS1BSKP1SKP2PTPN11PIK3CA | |
| SCHEMBL27029442 | 0.86 | ACHE (0.55) | CKS1BSKP1SKP2PTPN11PIK3CA | |
| SCHEMBL30718211 | 0.86 | ACHE (0.55) | CKS1BSKP1SKP2PTPN11PIK3CA | |
| SCHEMBL30718220 | 0.85 | GPR119 (0.51) | CKS1BSKP1SKP2PTPN11PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |