Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718225 | 0.84 | DGAT1 (0.39) | MAPTSMN1; SMN2KMT2ATDP1ADORA2A | |
| SCHEMBL29747064 | 0.73 | F11 (0.35) | MAPTALDH1A1SMN1; SMN2KDM4EIGF1R | |
| SCHEMBL30718282 | 0.73 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29126163 | 0.73 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29126115 | 0.73 | DGAT1 (0.32) | MAPTDGAT1 | |
| SCHEMBL30718277 | 0.73 | DGAT1 (0.32) | MAPTDGAT1 | |
| SCHEMBL29126148 | 0.72 | LRRK2 (0.41) | — | |
| SCHEMBL12179349 | 0.70 | PTK2 (0.47) | CAMKK2IGF1REGFRFGFR1JAK2 | |
| SCHEMBL2595092 | 0.68 | EGFR (0.50) | CAMKK2IGF1REGFRFGFR1JAK2 | |
| SCHEMBL22252552 | 0.67 | DGAT1 (0.35) | IGF1REGFRDGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247387-A | Aromatic heterocyclic compound and preparation method thereof | 上海翊石医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |