Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29126163 | 1.00 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29126151 | 0.78 | HSP90AA1 (0.40) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29126098 | 0.76 | LRRK2 (0.40) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL30718280 | 0.73 | MAPT (0.39) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27116596 | 0.71 | PIK3CG (0.61) | KMT2APIK3CGGSK3BCAMKK2EGFR | |
| SCHEMBL30718279 | 0.71 | LRRK2 (0.75) | LRRK2IGF1R | |
| SCHEMBL11813903 | 0.67 | MAPT (0.83) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL4544833 | 0.67 | KCNH3 (0.59) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL6237782 | 0.66 | MAPT (0.93) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL29609022 | 0.66 | MAPT (0.93) | MAPTALDH1A1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247387-A | Aromatic heterocyclic compound and preparation method thereof | 上海翊石医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |