Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GOT1 | P17174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072439 | 1.00 | HSD11B1 (0.35) | HSD11B1MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL31361277 | 0.81 | ALDH1A1 (0.38) | HSD11B1ALDH1A1 | |
| SCHEMBL31361287 | 0.77 | CYP1A2 (0.36) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL12491276 | 0.74 | TRPM8 (0.33) | HSD11B1ALDH1A1POLB | |
| SCHEMBL12491359 | 0.74 | TRPM8 (0.34) | HSD11B1 | |
| SCHEMBL31082851 | 0.72 | CYP2A6 (0.33) | — | |
| SCHEMBL15788366 | 0.71 | PARG (0.37) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL3990597 | 0.66 | CYP3A4 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL31083081 | 0.65 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL18876196 | 0.64 | HSD11B1 (0.34) | HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161346-A | Pyrrolo-ring compound and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118619943-A | Heteroaromatic ring compound, pharmaceutical composition and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| WO-2024006559-A1 | MODULATORS OF NLRP3 INFLAMMASOME AND RELATED PRODUCTS AND METHODS | Neumora Therapeutics, Inc. (US) | 2024-01-04 | — | — | WO | disclosed |