Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146850 | 1.00 | BACE1 (0.45) | BACE1MEN1KMT2ACDC7PIM1 | |
| SCHEMBL19411398 | 0.89 | BACE1 (0.43) | BACE1MEN1KMT2ACDC7PIM1 | |
| SCHEMBL27150635 | 0.89 | BACE1 (0.52) | BACE1MEN1KMT2APOLBKCNH2 | |
| SCHEMBL30718832 | 0.89 | BACE1 (0.52) | BACE1MEN1KMT2APOLBKCNH2 | |
| SCHEMBL27108966 | 0.81 | BACE1 (0.45) | BACE1POLBKCNH2HRH3IDO1 | |
| SCHEMBL31413431 | 0.81 | BACE1 (0.45) | BACE1POLBKCNH2HRH3IDO1 | |
| SCHEMBL7954797 | 0.78 | TLR9 (0.44) | MEN1KMT2AHRH4NPC1RAB9A | |
| SCHEMBL21000902 | 0.77 | MEN1 (0.57) | MEN1KMT2AHRH4NPC1RAB9A | |
| SCHEMBL29733200 | 0.77 | MEN1 (0.57) | MEN1KMT2AHRH4NPC1RAB9A | |
| SCHEMBL8359684 | 0.76 | HPGDS (0.46) | CDC7PIM1CSNK2BCSNK2A1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |