Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 9/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21853647 | 0.89 | HPGDS (0.45) | HPGDSMAPK8MAPK10 | |
| SCHEMBL25851400 | 0.77 | HPGDS (0.38) | HPGDSMAPK8MAPK10 | |
| SCHEMBL31127661 | 0.76 | OPRM1 (0.41) | HRH4PIM1CDC7CSNK2BCSNK2A1 | |
| SCHEMBL3063348 | 0.76 | OPRM1 (0.41) | HRH4PIM1CDC7CSNK2BCSNK2A1 | |
| SCHEMBL27146850 | 0.76 | BACE1 (0.45) | HRH4PIM1TLR9TLR8TLR7 | |
| SCHEMBL30718696 | 0.76 | BACE1 (0.45) | HRH4PIM1TLR9TLR8TLR7 | |
| SCHEMBL19411398 | 0.74 | BACE1 (0.43) | HRH4PIM1TLR9TLR8TLR7 | |
| SCHEMBL274998 | 0.74 | SLC6A2 (0.41) | HPGDSHRH4PRMT5 | |
| SCHEMBL8355547 | 0.70 | PRMT5 (0.48) | HPGDSPRMT5 | |
| SCHEMBL4923752 | 0.68 | SMN1; SMN2 (0.40) | CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919792-A | Integrin antagonists | MERCK & CO., INC. (US) | 1999-07-06 | — | — | US | disclosed |