Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | BRS3 | P32247 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346613 | 1.00 | TRPV4 (0.40) | TRPV4PDE2AKMT2ACCR5CTSS | |
| SCHEMBL30719552 | 0.91 | TRPV4 (0.39) | TRPV4PDE2AKMT2ACCR5CTSS | |
| SCHEMBL30719563 | 0.91 | TRPV4 (0.39) | TRPV4PDE2AKMT2ACCR5CTSS | |
| SCHEMBL27346590 | 0.91 | TRPV4 (0.39) | TRPV4PDE2AKMT2ACCR5CTSS | |
| SCHEMBL26065190 | 0.90 | KMT2A (0.39) | TRPV4KMT2A | |
| SCHEMBL25369209 | 0.88 | TRPV4 (0.38) | TRPV4PDE2AKMT2ABRS3 | |
| SCHEMBL30567127 | 0.88 | TRPV4 (0.38) | TRPV4PDE2AKMT2ABRS3 | |
| SCHEMBL27346611 | 0.82 | PDE2A (0.33) | PDE2A | |
| SCHEMBL26065201 | 0.80 | KMT2A (0.38) | TRPV4KMT2ALMNA | |
| SCHEMBL27346641 | 0.80 | TRPV4 (0.41) | TRPV4CCR5BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554934-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |