Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BRS3 | P32247 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719552 | 1.00 | TRPV4 (0.39) | TRPV4PDE2AKMT2ACTSSCCR5 | |
| SCHEMBL30719563 | 1.00 | TRPV4 (0.39) | TRPV4PDE2AKMT2ACTSSCCR5 | |
| SCHEMBL30719527 | 0.91 | TRPV4 (0.40) | TRPV4PDE2AKMT2ACTSSCCR5 | |
| SCHEMBL27346613 | 0.91 | TRPV4 (0.40) | TRPV4PDE2AKMT2ACTSSCCR5 | |
| SCHEMBL26065201 | 0.90 | KMT2A (0.38) | TRPV4KMT2ALMNA | |
| SCHEMBL25370116 | 0.88 | TRPV4 (0.37) | TRPV4PDE2AKMT2A | |
| SCHEMBL30567075 | 0.88 | TRPV4 (0.37) | TRPV4PDE2AKMT2A | |
| SCHEMBL27346587 | 0.83 | PDE2A (0.32) | PDE2A | |
| SCHEMBL30719473 | 0.81 | TRPV4 (0.40) | TRPV4BRS3 | |
| SCHEMBL27346583 | 0.81 | TRPV4 (0.40) | TRPV4BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |