Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065190 | 0.91 | KMT2A (0.39) | KMT2ATRPV4ALDH1A1MEN1KDM4E | |
| SCHEMBL27346590 | 0.90 | TRPV4 (0.39) | KMT2ATRPV4LMNA | |
| SCHEMBL30719552 | 0.90 | TRPV4 (0.39) | KMT2ATRPV4LMNA | |
| SCHEMBL30719563 | 0.90 | TRPV4 (0.39) | KMT2ATRPV4LMNA | |
| SCHEMBL25370116 | 0.89 | TRPV4 (0.37) | KMT2ATRPV4 | |
| SCHEMBL30567075 | 0.89 | TRPV4 (0.37) | KMT2ATRPV4 | |
| SCHEMBL30719527 | 0.80 | TRPV4 (0.40) | KMT2ATRPV4LMNA | |
| SCHEMBL27346613 | 0.80 | TRPV4 (0.40) | KMT2ATRPV4LMNA | |
| SCHEMBL26065199 | 0.80 | TRPV4 (0.37) | KMT2ATRPV4ALDH1A1MEN1KDM4E | |
| SCHEMBL25369209 | 0.80 | TRPV4 (0.38) | KMT2ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |