Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | AGER | Q15109 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31265696 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL698990 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL14861469 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL3389125 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL27994859 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL3421959 | 0.79 | MKNK1 (0.52) | KDM4EMAPTCYP3A4ALOX15TSHR | |
| SCHEMBL31469002 | 0.79 | MKNK1 (0.52) | KDM4EMAPTCYP3A4ALOX15TSHR | |
| SCHEMBL2323790 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL7812554 | 0.79 | L3MBTL1 (0.57) | KDM4EALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL3390642 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1MAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343361-A | Surface engineered extracellular vesicles and therapeutic uses thereof | 转变生物公司 | 2025-01-21 | — | — | CN | disclosed |
| CN-114127059-B | Macrocyclic chelators and methods of use thereof | 詹森生物科技公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-117396206-A | Compounds for the treatment of NASH and NAFLD | 吉利德科学公司 | 2024-01-12 | — | — | CN | disclosed |