Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264270 | 0.85 | HCRTR2 (0.50) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL30775045 | 0.85 | HCRTR2 (0.50) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL607037 | 0.83 | HCRTR2 (0.49) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| Lithium SCHEMBL607039 | 0.83 | HCRTR2 (0.49) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL16041105 | 0.83 | HCRTR2 (0.43) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL30719725 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL3385678 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL30775055 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1L3MBTL1HCRTR1HCRTR2 | |
| SCHEMBL2406304 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL11381734 | 0.80 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144760-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144760-A1 | NOVEL COMPOUNDS | HTR3B, HTR1B, HTR2B | KDM4E 1224/4885ALDH1A1 882/4885MAPT 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.