Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 16/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SCN4A | P35499 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619656 | 0.81 | LMNA (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL9332938 | 0.81 | LMNA (0.58) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7980250 | 0.78 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11306313 | 0.76 | NOX1 (0.65) | MEN1KMT2A | |
| SCHEMBL18637944 | 0.75 | HSD17B3 (0.53) | P2RX4MEN1KMT2ALMNATSHR | |
| Carbamazepine SCHEMBL28220906 | 0.74 | LMNA (0.92) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL2211282 | 0.74 | LMNA (0.64) | P2RX4LMNATSHRMAPK1SCN4A | |
| Hydrochloric Acid SCHEMBL5862630 | 0.74 | P2RX4 (0.66) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL21639 | 0.74 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL6477112 | 0.74 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773277-B | Synthesis method of 4H-1,2, 4-benzothiadiazine-1, 1-dioxide derivative | 兰州大学 | 2023-12-05 | — | — | CN | disclosed |