Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SCN4A | P35499 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | P2RX4 | Q99571 | 16/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30719756 | 0.81 | P2RX4 (0.62) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL9332938 | 0.81 | LMNA (0.58) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL11620818 | 0.77 | MAPK1 (0.36) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL1001947 | 0.76 | BCHE (0.63) | — | |
| SCHEMBL9419649 | 0.76 | P2RX4 (0.59) | P2RX4P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL10653232 | 0.74 | LMNA (0.39) | LMNATSHRMAPK1SCN4ASCN5A | |
| Hydrochloric Acid SCHEMBL5862630 | 0.74 | P2RX4 (0.66) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL6477112 | 0.74 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL29433237 | 0.74 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL2211282 | 0.74 | LMNA (0.64) | LMNATSHRMAPK1SCN4ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076812-A | 10-Halogeno- or 10,11-dihalogeno derivatives of 5H-dibenz[b,f]azepine | CIBA-GEIGY CORPORATION (US) | 1978-02-28 | — | — | US | disclosed |