Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SCN4A | P35499 | 1/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.64 |
| ▸ | P2RX4 | Q99571 | 16/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112131 | 0.81 | P2RX4 (0.53) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL11108253 | 0.81 | P2RX4 (0.47) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL11116807 | 0.81 | P2RX4 (0.47) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL11129965 | 0.80 | P2RX4 (0.47) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL29433237 | 0.78 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL21639 | 0.78 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL29360181 | 0.78 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A | |
| Hydrochloric Acid SCHEMBL5862630 | 0.78 | P2RX4 (0.66) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL6477112 | 0.78 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A | |
| Carbamazepine SCHEMBL31685158 | 0.78 | LMNA (1.00) | LMNATSHRMAPK1SCN4ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698602-B1 | Process for the preparation of 5-chlorocarbonyl-5H-dibenz(b,f)azepine | AWD PHARMA GMBH & CO KG (DE) | 2002-02-06 | — | — | EP | claimed |
| EP-0485685-B1 | Process for the preparation of 5-carbamoyl-5H-dibenz-[B,F]-azepine | DRESDEN ARZNEIMITTEL (DE) | 1998-08-05 | — | — | EP | claimed |
| EP-0423679-B1 | Process for the preparation of 5-(carbamoyl)-5H-dibenz[b,f]azepines | ALKALOIDA VEGYESZETI GYAR (HU) | 1994-04-27 | — | — | EP | claimed |
| US-5110923-A | METHOD FOR PREPARING 5-CHLOROCARBONYL-5H-DIBENZ(B,F)AZEPINE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1992-05-05 | — | — | US | claimed |
| EP-0423679-A2 | Process for the preparation of 5-(carbamoyl)-5H-dibenz[b,f]azepines | ALKALOIDA VEGYESZETI GYAR (HU) | 1991-04-24 | — | — | EP | claimed |
| CN-111201215-B | Novel amide compound, pin1 inhibitor using same, therapeutic agent for inflammatory disease, and therapeutic agent for cancer | 国立大学法人广岛大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-116354884-A | High-purity 10-methoxy iminostilbene and high-yield preparation method thereof | 浙江华洋药业有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-11529357-B2 | Injectable carbamazepine composition essentially free of 10-bromo-carbamazepine | H. LUNDBECK A/S (DK) | 2022-12-20 | — | — | US | disclosed |
| US-11504379-B2 | Amide compound, and Pin1 inhibitor, therapeutic agent for inflammatory diseases and therapeutic agent for cancer that use the same | HIROSHIMA UNIVERSITY (JP) | 2022-11-22 | — | — | US | disclosed |
| CN-113045643-B | Carbamazepine antigen and preparation method thereof | 杭州隆基生物技术有限公司 | 2022-05-10 | — | — | CN | disclosed |
| US-20210395231-A1 | RECEPTOR INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2021-12-23 | — | — | US | disclosed |
| US-20210054007-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2021-02-25 | — | — | US | disclosed |
| US-4447529-A | IMMUNOASSAY; AMINOGLYCOSIDE ANTIBIOTICS; STRIPS | MILES LABORATORIES, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4436660-A | Process for the production of 5-cyano-and 5-carboxamido-5H-dibenz[b,f]azepines | CIBA-GEIGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4404366-A | ENZYME CLEAVABLE GLYCOSIDIC LINKAGE | MILES LABORATORIES, INC. (US) | 1983-09-13 | — | — | US | disclosed |
| US-4331590-A | β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4279992-A | Specific binding assay employing an enzyme-cleavable substrate as label | MILES LABORATORIES, INC. (US) | 1981-07-21 | — | — | US | disclosed |
| US-4076707-A | N-(2-hexamethyleniminoethyl)-5H-dibenz[b,f]-azepine-5-carboxamides and quaternary ammonium derivatives thereof | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4076707-A | N-(2-hexamethyleniminoethyl)-5H-dibenz[b,f]-azepine-5-carboxamides and quaternary ammonium derivatives thereof | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4058511-A | Tegretol antigens and antibodies | SYVA COMPANY (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395231-A1 | RECEPTOR INHIBITORS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF | TACR1, TACR2, GPBAR1 | LMNA 4650/4885TSHR 202/4885MAPK1 1258/4885 |
| US-11529357-B2 | Injectable carbamazepine composition essentially free of 10-bromo-carbamazepine | APOB, PDE10A, SCN10A | LMNA 3326/4885TSHR 3238/4885MAPK1 4853/4885 |
| US-11504379-B2 | Amide compound, and Pin1 inhibitor, therapeutic agent for inflammatory diseases and therapeutic agent for cancer that use the same | PIN1, FKBP1A, FKBP5 | LMNA 3799/4885TSHR 4561/4885MAPK1 121/4885 |
| US-20210054007-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | TACR1, TACR2, GPBAR1 | LMNA 4605/4885TSHR 261/4885MAPK1 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.