Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720085 | 1.00 | NCF1 (0.44) | NCF1DDB1CRBNMAOBTGFBR2 | |
| SCHEMBL16411600 | 0.77 | MAPT (0.48) | MAPT | |
| SCHEMBL7914425 | 0.72 | CCR1 (0.42) | DDB1CRBNPIK3CBCYP2A6PDE10A | |
| SCHEMBL21088595 | 0.71 | DHFR (0.46) | MAOBMAPT | |
| SCHEMBL30545112 | 0.71 | DDB1 (0.39) | DDB1CRBNPIK3CBCYP2A6 | |
| SCHEMBL22323347 | 0.71 | DDB1 (0.39) | DDB1CRBNPIK3CBCYP2A6 | |
| SCHEMBL30503575 | 0.71 | APP (0.42) | DDB1CRBNMAPTPIK3CBCYP2A6 | |
| SCHEMBL15091312 | 0.71 | PIK3CB (0.44) | NCF1DDB1CRBNPIK3CBCYP2A6 | |
| SCHEMBL30322466 | 0.71 | DDB1 (0.39) | DDB1CRBNPIK3CBCYP2A6 | |
| SCHEMBL3754475 | 0.71 | DDB1 (0.39) | DDB1CRBNPIK3CBCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119255992-A | Heterocyclic derivatives, compositions and uses thereof | 北京丹擎医药科技有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2023226964-A1 | HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |