Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | CCNK | O75909 | 1/20 | 0.30 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | IL1B | P01584 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720221 | 0.82 | MGLL (0.56) | MGLLHCRTR1 | |
| SCHEMBL27246318 | 0.82 | MGLL (0.56) | MGLLHCRTR1 | |
| SCHEMBL30013286 | 0.82 | MGLL (0.57) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL27246228 | 0.82 | MGLL (0.57) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30012723 | 0.81 | MGLL (0.55) | MGLLHCRTR2HCRTR1 | |
| SCHEMBL27142650 | 0.81 | MGLL (0.55) | MGLLHCRTR2HCRTR1 | |
| SCHEMBL25326138 | 0.80 | DRD2 (0.37) | MGLLDRD2DRD3HCRTR2HCRTR1 | |
| SCHEMBL30553287 | 0.80 | DRD2 (0.37) | MGLLDRD2DRD3HCRTR2HCRTR1 | |
| SCHEMBL27148904 | 0.80 | MGLL (0.67) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30012082 | 0.79 | MGLL (0.54) | MGLLCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |