SCHEMBL30720883

SCHEMBL30720883

CCCCc1nc(C(F)F)cn1Cc1ncc(Cl)cn1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.36
AGER Q15109 2/20 0.34
RXRA P19793 2/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2B Q13224 2/20 0.31
AGTR1 P30556 1/20 0.31
AGTR2 P50052 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30720861 0.83 KCNH2 (0.38) KCNH2AGERRXRAGRIN1GRIN2B
SCHEMBL30720877 0.78 AGER (0.36) KCNH2AGER
SCHEMBL26090792 0.76 RXRA (0.32) RXRAGRIN1GRIN2B
SCHEMBL30720854 0.74 AGER (0.34) KCNH2AGERNPC1RAB9ASMN1; SMN2
SCHEMBL26091325 0.73 PTGS2 (0.33) RXRAGRIN1GRIN2B
SCHEMBL26088968 0.72 PTGS2 (0.37) RXRAGRIN1GRIN2BSMN1; SMN2
SCHEMBL30720878 0.71 GRIN2B (0.32) KCNH2GRIN2B
SCHEMBL27348270 0.70
SCHEMBL30361048 0.70 GRIN2B (0.34) RXRAGRIN1GRIN2B
SCHEMBL30361045 0.70 GRIN2B (0.34) RXRAGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554933-A1 HERBICIDAL IMIDAZOLE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-05-21 EP disclosed
CN-119451949-A Herbicidal imidazole compounds 先正达农作物保护股份公司 2025-02-14 CN disclosed
WO-2024013018-A1 HERBICIDAL IMIDAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-01-18 WO disclosed