SCHEMBL30720985

SCHEMBL30720985

COc1ccc(N2C(=O)c3ccc4c5ccc6c7c(ccc(c8ccc(c3c48)C2=O)c75)C(=O)N(c2ccc(OC)cc2)C6=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.59
NR1H3 Q13133 2/20 0.55
KMT2A Q03164 6/20 0.53
MEN1 O00255 5/20 0.52
POLB P06746 2/20 0.51
APAF1 O14727 1/20 0.51
MGLL Q99685 1/20 0.51
ALDH1A1 P00352 2/20 0.49
PGR P06401 1/20 0.48
MAPT P10636 1/20 0.48
MAPK1 P28482 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KDM4E B2RXH2 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3404909 1.00 ESR1 (0.59) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL29355675 1.00 ESR1 (0.59) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL15672159 0.94 ESR1 (0.57) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL5578422 0.94 ESR1 (0.54) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL12639210 0.93 ESR1 (0.66) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL7647376 0.90 KMT2A (0.58) ESR1NR1H3KMT2AMEN1ALDH1A1
SCHEMBL12577485 0.89 NR1H3 (0.56) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL12341700 0.87 ESR1 (0.63) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL14124834 0.87 ESR1 (0.48) ESR1NR1H3KMT2AMEN1POLB
SCHEMBL14125027 0.87 ESR1 (0.48) ESR1NR1H3KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048528-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF XEROX CORPORATION (US) 2026-02-19 US disclosed
US-11801617-B2 Optical absorbing thermoplastic polymer particles and methods of production and uses thereof XEROX CORPORATION (US) 2023-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048528-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF SPOP, RAB5IF, CETP ESR1 3109/4885NR1H3 1335/4885KMT2A 3342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.