Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355675 | 0.94 | ESR1 (0.59) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL3404909 | 0.94 | ESR1 (0.59) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL30720985 | 0.94 | ESR1 (0.59) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL15672159 | 0.88 | ESR1 (0.57) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL12639210 | 0.87 | ESR1 (0.66) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL7647376 | 0.85 | KMT2A (0.58) | ESR1NR1H3KMT2AMEN1ALDH1A1 | |
| SCHEMBL12577485 | 0.83 | NR1H3 (0.56) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL14124834 | 0.81 | ESR1 (0.48) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL12341700 | 0.81 | ESR1 (0.63) | ESR1NR1H3KMT2AMEN1POLB | |
| SCHEMBL14125027 | 0.81 | ESR1 (0.48) | ESR1NR1H3KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032640-A1 | Cytokine receptor | LUDWIG INSTITUE FOR CANCER RESEARCH (AU) | 2007-02-08 | — | — | US | disclosed |
| US-20070032640-A1 | Cytokine receptor | LUDWIG INSTITUE FOR CANCER RESEARCH (AU) | 2007-02-08 | — | — | US | disclosed |
| US-20070032640-A1 | Cytokine receptor | LUDWIG INSTITUE FOR CANCER RESEARCH (AU) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032640-A1 | Cytokine receptor | IL6ST, IL6, IL1RN | ESR1 1019/4885NR1H3 510/4885KMT2A 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.