Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 10/20 | 0.33 |
| ▸ | EGFR | P00533 | 6/20 | 0.32 |
| ▸ | SRC | P12931 | 5/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | PRKACG | P22612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22301636 | 1.00 | CYP11B2 (0.35) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL20570729 | 0.92 | MAP3K8 (0.32) | CYP11B2MAP3K8EGFRERBB2 | |
| SCHEMBL20571102 | 0.86 | MAP3K8 (0.34) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL25636706 | 0.82 | CYP11B2 (0.35) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL19889982 | 0.80 | KHK (0.36) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL28652978 | 0.79 | CSNK2A1 (0.35) | — | |
| SCHEMBL19877263 | 0.78 | CYP11B2 (0.35) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL19877026 | 0.78 | CYP11B2 (0.36) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL23899093 | 0.77 | SRC (0.37) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 | |
| SCHEMBL19877781 | 0.77 | CYP11B2 (0.41) | CYP11B2MAP3K8EGFRSRCMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563323-B | Benzothiazolyl biaryl compound, preparation method and application | 上海凌达生物医药有限公司 | 2023-12-01 | — | — | CN | disclosed |