SCHEMBL30722995

SCHEMBL30722995

NC(Cc1ccc(-c2ccccc2)nc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TPH1 P17752 9/20 0.60
▸ SLC7A5 Q01650 2/20 0.57
▸ ALPI P09923 1/20 0.57
▸ PKM P14618 1/20 0.57
▸ PTGS1 P23219 1/20 0.57
▸ XIAP P98170 1/20 0.57
▸ HSD17B10 Q99714 1/20 0.53
▸ CYP11B1 P15538 3/20 0.50
▸ CYP11B2 P19099 3/20 0.50
▸ LDHA P00338 1/20 0.49
▸ GRIA2 P42262 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25357127 1.00 TPH1 (0.60) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL25356472 1.00 TPH1 (0.60) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL31303988 1.00 TPH1 (0.60) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL25356476 1.00 TPH1 (0.60) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL31370046 0.89 CYP11B1 (0.52) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL27122562 0.87 NPC1 (0.63) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL26966050 0.87 NPC1 (0.63) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL31523921 0.87 NPC1 (0.63) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL31688759 0.86 GRIA2 (0.65) TPH1SLC7A5ALPIPKMPTGS1
SCHEMBL12273163 0.85 SLC7A5 (0.54) TPH1SLC7A5ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 — — EP disclosed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 — — EP disclosed
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PEPTIDREAM INC. (JP) 2025-11-27 — — US disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 — — WO disclosed
EP-4541805-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT PeptiDream Inc. (JP) 2025-04-23 — — EP disclosed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 — — WO disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 — — WO disclosed
WO-2023243120-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT ペプチドリーム株式会社 2023-12-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361274-A1 PEPTIDE AND PEPTIDE-CONTAINING AGENT BMP4, BMP1, BMPR2 TPH1 4441/4885SLC7A5 2541/4885ALPI 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback