Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723469 | 0.86 | MAPT (0.44) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723442 | 0.86 | MAPT (0.44) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723461 | 0.85 | PDK1 (0.41) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723440 | 0.83 | SIRT1 (0.41) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723445 | 0.83 | GBA1 (0.43) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723511 | 0.82 | KMT2A (0.40) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723528 | 0.82 | KMT2A (0.40) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30892168 | 0.81 | NR1H2 (0.42) | ABCB1PDK1PDK2PDK3PDK4 | |
| SCHEMBL30723543 | 0.81 | PDK1 (0.40) | PDK1PDK2PDK3PDK4CHRM2 | |
| SCHEMBL30723476 | 0.81 | NR1H2 (0.42) | ABCB1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430619-A | Pyrazolopyridine compound and preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-01-23 | — | — | CN | disclosed |