Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723486 | 0.83 | ABCB1 (0.41) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL3580101 | 0.72 | OPRM1 (0.44) | MAPT | |
| SCHEMBL22208222 | 0.72 | OPRM1 (0.44) | MAPT | |
| SCHEMBL30064999 | 0.72 | OPRM1 (0.44) | MAPT | |
| SCHEMBL22555109 | 0.72 | OPRM1 (0.44) | MAPT | |
| SCHEMBL23646070 | 0.69 | PDK1 (0.52) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| SCHEMBL13732798 | 0.69 | PDK1 (0.52) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| SCHEMBL23646112 | 0.69 | PDK1 (0.52) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| SCHEMBL26694780 | 0.69 | GBA1 (0.45) | GBA1MAPT | |
| SCHEMBL9170865 | 0.69 | MAPT (0.49) | GBA1DRD2DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430619-A | Pyrazolopyridine compound and preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-01-23 | — | — | CN | disclosed |