Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | PDE8A | O60658 | 4/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212692 | 0.77 | MBOAT4 (0.33) | HTR2AHTR2CHTR2BTLR8REN | |
| SCHEMBL16703136 | 0.74 | SCN9A (0.33) | HTR2AHTR2CHTR2BSCN9AREN | |
| SCHEMBL18205343 | 0.74 | PDE8A (0.32) | PDE8APDE2APDE4DKCNH2PDE10A | |
| SCHEMBL29778825 | 0.72 | BACE1 (0.33) | HTR2AHTR2CHTR2BPDE8ATLR8 | |
| SCHEMBL21608759 | 0.72 | BACE1 (0.33) | HTR2AHTR2CHTR2BPDE8ATLR8 | |
| SCHEMBL30723514 | 0.71 | P2RX3 (0.36) | HTR2ATLR8SCN9ARENCTSD | |
| SCHEMBL21608777 | 0.71 | P2RX3 (0.36) | HTR2ATLR8SCN9ARENCTSD | |
| SCHEMBL22235500 | 0.69 | HTT (0.46) | HTR2AHTR2CHTR2BTLR8 | |
| SCHEMBL23915311 | 0.67 | BACE1 (0.36) | HTR2AHTR2CHTR2BSCN9AREN | |
| SCHEMBL23641518 | 0.67 | SCN9A (0.38) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112292375-B | Substituted alkoxypyridinyl indole sulfonamides | 优时比制药有限公司 | 2023-12-05 | — | — | CN | disclosed |