Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817117 | 0.81 | KIF11 (0.32) | KIF11 | |
| SCHEMBL17157399 | 0.79 | GPR3 (0.42) | KDM1AKDM1BKIF11 | |
| SCHEMBL7639560 | 0.77 | KIF11 (0.31) | KIF11 | |
| SCHEMBL20244888 | 0.77 | SLC6A4 (0.39) | KDM1AKDM1BKIF11 | |
| SCHEMBL8472537 | 0.76 | KDM1A (0.31) | KDM1AKDM1B | |
| SCHEMBL3818720 | 0.74 | ALDH1A1 (0.39) | KIF11 | |
| SCHEMBL615534 | 0.74 | VEGFA (0.33) | — | |
| SCHEMBL12180436 | 0.74 | KIF11 (0.40) | KIF11 | |
| SCHEMBL29706886 | 0.74 | VEGFA (0.33) | — | |
| SCHEMBL5839939 | 0.73 | KIF11 (0.33) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |