Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769196 | 0.93 | MEN1 (0.48) | MTNR1AMTNR1BHDAC1HDAC6KDM4E | |
| SCHEMBL1858307 | 0.84 | MTNR1A (0.53) | MTNR1AMTNR1BHDAC1HDAC6KMT2A | |
| SCHEMBL28820181 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BHDAC1HDAC6MEN1 | |
| SCHEMBL28020307 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BHDAC1HDAC6MEN1 | |
| SCHEMBL14286887 | 0.79 | CYSLTR2 (0.58) | MTNR1AMTNR1BHDAC1HDAC6CHRM2 | |
| SCHEMBL4987223 | 0.76 | MTNR1A (0.48) | MTNR1AMTNR1BHDAC1HDAC6CHRM2 | |
| SCHEMBL5077290 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1BHDAC1HDAC6CHRM2 | |
| SCHEMBL27508418 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1BHDAC1HDAC6CHRM2 | |
| SCHEMBL1856039 | 0.75 | L3MBTL1 (0.50) | MTNR1AMTNR1BHDAC1HDAC6MEN1 | |
| SCHEMBL7062570 | 0.74 | MMP3 (0.45) | KDM4EPPARGPPARAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |