SCHEMBL30724468

SCHEMBL30724468

CC(C)c1ccc(O[Si](C(C)C)(C(C)C)C(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
RAB9A P51151 2/20 0.38
IDO1 P14902 2/20 0.38
TYR P14679 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
XBP1 P17861 1/20 0.34
GRM5 P41594 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15708075 0.82 TDP1 (0.46) MEN1KMT2ARAB9ASMN1; SMN2MAPT
SCHEMBL198322 0.82 L3MBTL1 (0.41) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL3606473 0.79 KDM4E (0.33) LMNAALDH1A1
SCHEMBL3606470 0.79 KDM4E (0.33) LMNAALDH1A1
SCHEMBL3807540 0.79 ADRB2 (0.38) SMN1; SMN2LMNAHPGD
SCHEMBL13043497 0.79 ACHE (0.44) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL15974976 0.77 ESR2 (0.44) MEN1KMT2ARAB9ATYRMAPT
SCHEMBL15974368 0.77
SCHEMBL20594015 0.77
SCHEMBL481885 0.77 MAPT (0.37) MEN1KMT2ARAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023248253-A1 A NEW LIGAND SCAFFOLD (PY-PYRI) FOR THE META BORYLATION OF PHENOL DERIVATIVES CENTRE OF BIOMEDICAL RESEARCH (IN) 2023-12-28 WO disclosed