Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724683 | 0.87 | HDAC8 (0.41) | HDAC8HDAC6 | |
| SCHEMBL30798351 | 0.85 | HDAC8 (0.42) | HDAC8HRH4NPC1POLBRAB9A | |
| SCHEMBL91469 | 0.77 | CTSK (0.49) | HRH4NPSR1 | |
| SCHEMBL91478 | 0.74 | CTSK (0.58) | HRH4 | |
| SCHEMBL91484 | 0.73 | CTSK (0.60) | HRH4 | |
| SCHEMBL12367075 | 0.73 | IKBKB (0.61) | HRH4POLB | |
| SCHEMBL24065221 | 0.71 | CDK1 (0.54) | HRH4 | |
| SCHEMBL18677322 | 0.71 | CDK1 (0.54) | HRH4 | |
| SCHEMBL6508763 | 0.71 | IKBKB (0.58) | HRH4 | |
| SCHEMBL15830033 | 0.71 | MAPK1 (0.62) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |