Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195353 | 1.00 | HDAC8 (0.44) | HDAC8PRMT5OGG1HCAR3HDAC6 | |
| SCHEMBL23501005 | 0.87 | HDAC1 (0.44) | HDAC8PRMT5OGG1HDAC6KDM4E | |
| SCHEMBL27195442 | 0.82 | HDAC8 (0.40) | HDAC8PRMT5HCAR3KDM4ENPC1 | |
| SCHEMBL30724674 | 0.75 | SORT1 (0.42) | HDAC8PRMT5HCAR3HDAC6GBA1 | |
| SCHEMBL27195343 | 0.75 | SORT1 (0.42) | HDAC8PRMT5HCAR3HDAC6GBA1 | |
| SCHEMBL22092818 | 0.75 | HDAC6 (0.44) | HDAC8PRMT5HCAR3HDAC6GBA1 | |
| SCHEMBL23501092 | 0.72 | HDAC8 (0.41) | HDAC8PRMT5HDAC6KDM4EGBA1 | |
| SCHEMBL29878495 | 0.72 | HDAC8 (0.41) | HDAC8PRMT5HDAC6KDM4EGBA1 | |
| SCHEMBL30724693 | 0.72 | GAA (0.42) | PRMT5MEN1NPC1RAB9AKMT2A | |
| SCHEMBL27195418 | 0.72 | GAA (0.42) | PRMT5MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |