Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27195418 | 1.00 | GAA (0.42) | GAAMAPTTHRBMAPK1RXFP1 | |
| SCHEMBL27195442 | 0.85 | HDAC8 (0.40) | MAPTOPRK1PRMT5NPC1RAB9A | |
| SCHEMBL30724674 | 0.84 | SORT1 (0.42) | MAPTMAPK1PRMT5NPC1RAB9A | |
| SCHEMBL27195343 | 0.84 | SORT1 (0.42) | MAPTMAPK1PRMT5NPC1RAB9A | |
| SCHEMBL22092797 | 0.78 | HDAC8 (0.43) | GAAMAPK1RXFP1NPSR1OPRK1 | |
| SCHEMBL28653403 | 0.78 | HDAC8 (0.43) | GAAMAPK1RXFP1NPSR1OPRK1 | |
| SCHEMBL19190925 | 0.73 | NNMT (0.61) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL27195353 | 0.72 | HDAC8 (0.44) | RXFP1PRMT5NPC1RAB9AMEN1 | |
| SCHEMBL30724696 | 0.72 | HDAC8 (0.44) | RXFP1PRMT5NPC1RAB9AMEN1 | |
| SCHEMBL4231706 | 0.72 | P2RY12 (0.47) | GAAMAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |