Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 4/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724674 | 1.00 | SORT1 (0.42) | SORT1PRMT5HCAR3HDAC8GBA1 | |
| SCHEMBL27195418 | 0.84 | GAA (0.42) | PRMT5NPC1MAPTMAPK1RAB9A | |
| SCHEMBL30724693 | 0.84 | GAA (0.42) | PRMT5NPC1MAPTMAPK1RAB9A | |
| SCHEMBL30724696 | 0.75 | HDAC8 (0.44) | PRMT5HCAR3HDAC8GBA1HDAC6 | |
| SCHEMBL27195353 | 0.75 | HDAC8 (0.44) | PRMT5HCAR3HDAC8GBA1HDAC6 | |
| SCHEMBL25124228 | 0.75 | NOTUM (0.39) | PRMT5 | |
| SCHEMBL22092818 | 0.74 | HDAC6 (0.44) | PRMT5HCAR3HDAC8GBA1HDAC6 | |
| SCHEMBL30724677 | 0.74 | GBA1 (0.42) | PRMT5HDAC8GBA1HDAC6 | |
| SCHEMBL30724681 | 0.74 | GABRP (0.42) | SORT1PRMT5GBA1 | |
| SCHEMBL27195442 | 0.72 | HDAC8 (0.40) | PRMT5HCAR3HDAC8NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12145929-B2 | Piperidine derivative and pharmaceutical composition for inhibiting autotaxin comprising same | NEXTGEN BIOSCIENCE CO., LTD. (KR) | 2024-11-19 | — | — | US | disclosed |
| US-20240279216-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | NEXTGEN BIOSCIENCE CO., LTD. (KR) | 2024-08-22 | — | — | US | disclosed |
| EP-4353720-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2024-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279216-A1 | NOVEL PIPERIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING SAME | ENPP2, UACA, ITCH | SORT1 3532/4885PRMT5 2568/4885HCAR3 1694/4885 |
| US-12145929-B2 | Piperidine derivative and pharmaceutical composition for inhibiting autotaxin comprising same | ENPP2, UACA, ACAT2 | SORT1 3628/4885PRMT5 2490/4885HCAR3 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.