SCHEMBL30724713

SCHEMBL30724713

CN(CC(=O)N[C@@H](CCCCN)C(=O)O)C(=O)[C@H](Cc1cccnc1)NC(=O)[C@@H](N)CC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.41
▸ SLC15A2 Q16348 1/20 0.40
▸ KISS1R Q969F8 2/20 0.39
▸ F2 P00734 4/20 0.39
▸ ERAP2 Q6P179 2/20 0.39
▸ LNPEP Q9UIQ6 2/20 0.39
▸ PLG P00747 1/20 0.38
▸ PLAT P00750 1/20 0.38
▸ PRSS1 P07477 1/20 0.38
▸ MMP9 P14780 1/20 0.37
▸ MMP8 P22894 1/20 0.37
▸ FURIN P09958 1/20 0.37
▸ ERAP1 Q9NZ08 1/20 0.37
▸ F10 P00742 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30724705 0.84 LMNA (0.43) KISS1RMMP9MMP8
SCHEMBL27428949 0.84 LMNA (0.42) KISS1RMMP9MMP8
SCHEMBL30918324 0.84 LMNA (0.42) KISS1RMMP9MMP8
SCHEMBL27428883 0.83 LMNA (0.41) KISS1RMMP9MMP8
SCHEMBL29666227 0.80 ERAP2 (0.52) FOLH1SLC15A2ERAP2LNPEPERAP1
SCHEMBL30724704 0.79 GPR132 (0.48) FOLH1MMP9MMP8
SCHEMBL31167351 0.79 ERAP2 (0.51) FOLH1SLC15A2KISS1RERAP2LNPEP
SCHEMBL30724708 0.78 BACE1 (0.45) KISS1RMMP9MMP8
SCHEMBL30019030 0.78 ERAP2 (0.48) FOLH1SLC15A2KISS1RERAP2LNPEP
SCHEMBL31233783 0.76 ERAP2 (0.44) FOLH1SLC15A2KISS1RERAP2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547337-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS Sanofi (FR) 2025-05-07 — — EP disclosed
WO-2024003313-A9 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS SANOFI (FR) 2025-03-20 — — WO disclosed
WO-2024003313-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS SANOFI (FR) 2024-01-04 — — WO disclosed
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