SCHEMBL30725644

SCHEMBL30725644

CC(C)=CCc1c(O)ccc2c(=O)cc(-c3ccc(O)c(O)c3)oc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.73
TERT O14746 5/20 0.61
BRD4 O60885 1/20 0.61
PDE5A O76074 2/20 0.58
ESR1 P03372 1/20 0.58
PDE4D Q08499 1/20 0.58
ESR2 Q92731 1/20 0.58
PTGS1 P23219 2/20 0.55
PTGS2 P35354 1/20 0.55
MCL1 Q07820 1/20 0.55
CSNK2A2 P19784 1/20 0.53
CSNK2B P67870 1/20 0.53
CSNK2A1 P68400 1/20 0.53
SLC22A2 O15244 1/20 0.53
SLC22A1 O15245 1/20 0.53
PTPN1 P18031 3/20 0.52
TNKS O95271 1/20 0.50
PARP1 P09874 1/20 0.50
ALOX5 P09917 1/20 0.50
TNKS2 Q9H2K2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27013490 1.00 AKT1 (0.73) AKT1TERTBRD4PDE5AESR1
SCHEMBL4214011 0.91 PDE5A (0.71) AKT1TERTBRD4PDE5AESR1
SCHEMBL3192637 0.89 PDE5A (0.60) AKT1TERTBRD4PDE5AESR1
SCHEMBL3181663 0.88 PDE5A (0.59) AKT1TERTBRD4PDE5AESR1
SCHEMBL3188097 0.86 PDE5A (0.56) AKT1TERTBRD4PDE5AESR1
SCHEMBL3181023 0.85 PDE5A (0.56) AKT1TERTBRD4PDE5AESR1
SCHEMBL4828372 0.85 AKT1 (1.00) AKT1PDE5AESR1PDE4DESR2
SCHEMBL3174917 0.82 KDM4E (0.54) AKT1TERTPDE5AESR1PDE4D
SCHEMBL7374824 0.81 TERT (0.65) AKT1TERTBRD4MCL1CSNK2A2
SCHEMBL13532130 0.81 KDM4E (0.56) AKT1PDE5AESR1PDE4DESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543220-A2 COMPOSITIONS FOR REDUCING METHANE EMISSIONS, ANIMAL FEEDS COMPRISING THEM AND THEIR USE TO REDUCE METHANE EMISSIONS Mootral Innovations Limited (GB) 2025-04-30 EP claimed
WO-2023247942-A2 COMPOSITIONS FOR REDUCING METHANE EMISSION Mootral Innovations Limited (GB) 2023-12-28 WO claimed
EP-4543220-A2 COMPOSITIONS FOR REDUCING METHANE EMISSIONS, ANIMAL FEEDS COMPRISING THEM AND THEIR USE TO REDUCE METHANE EMISSIONS Mootral Innovations Limited (GB) 2025-04-30 EP disclosed
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2024-01-18 US disclosed
WO-2023247942-A2 COMPOSITIONS FOR REDUCING METHANE EMISSION Mootral Innovations Limited (GB) 2023-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016777-A1 COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS THPO, SERPINB1, SERPINC1 AKT1 4428/4885TERT 925/4885BRD4 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.